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Article

A single amino acid residue controls ROS production in the respiratory Complex I from Escherichia coli.

Molecular microbiology - 1 Dec 2013

Knuuti Juho, Belevich Galina, Sharma Vivek, Bloch Dmitry A, Verkhovskaya Marina

Abstract excerpt

Reactive oxygen species (ROS) production by respiratory Complex I from Escherichia coli was studied in bacterial membrane fragments and in the isolated and purified enzyme, either solubilized or incorporated in proteoliposomes. We found that the replacement of a single amino acid residue in close proximity to the nicotinamide adenine dinucleotide (NADH)-binding catalytic site (E95 in the NuoF subunit)...

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PMID: 24325249
DOI: 10.1111/mmi.12424

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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