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Article

Cytochrome P450 4F2 polymorphism in patients with liver cirrhosis.

Bulletin of experimental biology and medicine - 1 Dec 2013

Vavilin V A, Nepomnyashchikh D L, Shchepotina E G, Karavaeva Yu Yu, Makarova S I, Vinogradova E V, Kudryashov A V, Nokhrina Zh V, Lyakhovich V V

Abstract excerpt

1297C/T polymorphism of CYP4F2 gene was studied in 108 patients with chronic liver diseases. No significant correlation with predisposition to rapid liver cirrhosis was revealed without consideration for cirrhosis etiology (OR=0.93, 95% CI=0.28-2.99, p=0.885). In patients with viral cirrhosis, a tendency to association of 1297T allele genotypes with rapid cirrhosis development was found (OR=6.0, 95%...

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PMID: 24319743
DOI: 10.1007/s10517-013-2305-z

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