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Article

Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures.

Nature genetics - 1 Jan 2014

Lieberman Tami D, Flett Kelly B, Yelin Idan, Martin Thomas R, McAdam Alexander J, Priebe Gregory P, Kishony Roy

Abstract excerpt

Advances in sequencing technologies have enabled the identification of mutations acquired by bacterial pathogens during infection. However, it remains unclear whether adaptive mutations fix in the population or lead to pathogen diversification within the patient. Here we study the genotypic diver...

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Identifiers

PMID: 24316980
DOI: 10.1038/ng.2848
PMCID: PMC3979468

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24316980-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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