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Article

Multi-site saturation by OmniChange yields a pH- and thermally improved phytase.

Journal of biotechnology - 20 Jan 2014

Shivange Amol V, Dennig Alexander, Schwaneberg Ulrich

Abstract excerpt

Directed evolution of Yersinia mollaretii phytase (Ymphytase) yielded an improved variant SM2P3E4 (also named M1; D52N, T77K, K139E, G187S, V298M) in our previous study. Variant M1 retained high specific activity (993U/mg; equivalent to 93% of wild-type activity) and improved thermal resistance (T50 improved by 1.5°C compared to wild-type at 58°C; 20min incubation time), making variant M1 an attractive enzyme for...

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PMID: 24315971
DOI: 10.1016/j.jbiotec.2013.11.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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