Article
Effect of genetic mutations on outcomes of stem cell transplantation in children with hemophagocytic lymphohistiocytosis.
Bone marrow transplantation - 1 Jul 2025
Öztürk Gülyüz, Yeşilipek Mehmet Akif, Akçay Arzu, Uygun Vedat, Özek Gülcihan, Karasu Gülsün, Yılmaz Ebru, Demir Yenigürbüz Fatma, Öztürkmen Seda, Aksoylar Serap, Ok Bozkaya İkbal, Yalçın Koray, Adaklı Aksoy Başak, Ünal Ekrem, Akıncı Burcu, Daloğlu Hayriye, Karagün Barbaros Şahin, Kansoy Savaş, Özbek Namık, İnce Elif, Demir Hacı Ahmet, Gündoğdu Müge, Malbora Barış, Karakükçü Musa, Elli Murat, Akyay Arzu, Güneş Adalet Meral, Akbayram Sinan, Sarper Nazan, Del Castello Buket Erer, Hazar Volkan, Antmen Bülent
Abstract excerpt
Primary hemophagocytic lymphohistiocytosis (p-HLH) can be cured with allogeneic haematopoietic stem cell transplantation (allo-HSCT). It remains unclear whether HSCT outcomes are affected by the presence of different genetic mutations. We used data obtained from children who underwent allo-HSCT for HLH to examine the effects of genetic mutations on HSCT outcomes. Data from 153 paediatric patients in 18 paediatric...
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