Article
Characteristics and determinants of T-cell phenotype normalization in HIV-1-infected individuals receiving long-term antiretroviral therapy.
HIV medicine - 1 Mar 2014
Ndumbi P, Gillis J, Raboud J, Cooper C, Hogg R S, Montaner J S G, Burchell A N, Loutfy M R, Machouf N, Klein M B, Tsoukas C
Abstract excerpt
OBJECTIVES: Although combination antiretroviral therapy (cART) can restore CD4 T-cell numbers in HIV infection, alterations in T-cell regulation and homeostasis persist. We assessed the incidence and predictors of reversing these alterations with cART. METHODS: ART-naïve adults (n = 4459) followe...
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