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Article

The role of NOD2 in murine and human melioidosis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jan 2014

Myers Nicolle D, Chantratita Narisara, Berrington William R, Chierakul Wirongrong, Limmathurotsakul Direk, Wuthiekanun Vanaporn, Robertson Johanna D, Liggitt H Denny, Peacock Sharon J, Skerrett Shawn J, West T Eoin

Abstract excerpt

Nucleotide-binding oligomerization domain 2 (NOD2) is a cytosolic pathogen recognition receptor that regulates susceptibility to a variety of infections and chronic diseases. Burkholderia pseudomallei, a facultative intracellular bacterium, causes the tropical infection melioidosis. We hypothesized that NOD2 may participate in host defense in melioidosis. We performed a series of in vitro assays and in vivo...

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Identifiers

PMID: 24298015
DOI: 10.4049/jimmunol.1301436
PMCID: PMC3872087

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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