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Article

FoxO3a is an antimelanogenic factor that mediates antioxidant-induced depigmentation.

The Journal of investigative dermatology - 1 May 2014

Kim Juewon, Choi Hyunjung, Cho Eun-Gyung, Lee Tae R

Abstract excerpt

Forkhead box-O (FoxO) family transcriptional factors control the expression of many genes involved in a variety of cellular processes. Melanogenesis is an oxidizing process; therefore, many antioxidants are used to inhibit melanin production. However, their mechanism of action is poorly understood. In this study, we investigated the role of FoxO3a, which is a key factor in oxidative stress-related cellular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24284420
DOI: 10.1038/jid.2013.510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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