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Article

Investigations on the Tobacco Necrosis Virus D p60 replicase protein.

PloS one - 1 Jan 2013

Fang Liang, Coutts Robert H A

Abstract excerpt

Tobacco Necrosis Virus D (TNV-D), in the genus Betanecrovirus (family Tombusviridae), possesses a single-stranded, positive-sense RNA genome containing six open reading frames (ORFs). Two 5'-proximal ORFs (1 and 2) encode overlapping polypeptides of 22 and 82 kDa (p22 and p82, respectively) which are both required for replication. The p22 auxiliary protein contains no replication motifs but the C-terminal region,...

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PMID: 24278346
DOI: 10.1371/journal.pone.0080912
PMCID: PMC3836746

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