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Article

Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.

PLoS genetics - 1 Nov 2013

Beznosková Petra, Cuchalová Lucie, Wagner Susan, Shoemaker Christopher J, Gunišová Stanislava, von der Haar Tobias, Valášek Leoš Shivaya

Abstract excerpt

Translation is divided into initiation, elongation, termination and ribosome recycling. Earlier work implicated several eukaryotic initiation factors (eIFs) in ribosomal recycling in vitro. Here, we uncover roles for HCR1 and eIF3 in translation termination in vivo. A substantial proportion of eIF3, HCR1 and eukaryotic release factor 3 (eRF3) but not eIF5 (a well-defined "initiation-specific" binding partner of...

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Source

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Identifiers

PMID: 24278036
DOI: 10.1371/journal.pgen.1003962
PMCID: PMC3836723

Genes

ABCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells.PMID 24278036Read ↗

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