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Article

JAK2V617F allele burden is associated with thrombotic mechanisms activation in polycythemia vera and essential thrombocythemia patients.

International journal of hematology - 1 Jan 2014

Coucelo Margarida, Caetano Gonçalo, Sevivas Teresa, Almeida Santos Susana, Fidalgo Teresa, Bento Celeste, Fortuna Manuela, Duarte Marta, Menezes Cristina, Ribeiro M Letícia

Abstract excerpt

The clinical courses of polycythemia vera (PV) and essential thrombocythemia (ET) are characterized by thrombohemorrhagic diathesis. Several groups have suggested an association between JAK2V617F mutation and thrombosis. We hypothesized a relationship between JAK2V617F allele burden, cellular activation parameters, and thrombosis. We evaluated a group of PV and ET patients using flow cytometry: platelet CD62P,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24277659
DOI: 10.1007/s12185-013-1475-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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