The genetic relationship between handedness and neurodevelopmental disorders.

doi:10.1016/j.molmed.2013.10.008

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Article

The genetic relationship between handedness and neurodevelopmental disorders.

Trends in molecular medicine - 1 Feb 2014

Brandler William M, Paracchini Silvia

Abstract excerpt

Handedness and brain asymmetry have been linked to neurodevelopmental disorders such as dyslexia and schizophrenia. The genetic nature of this correlation is not understood. Recent discoveries have shown handedness is determined in part by the biological pathways that establish left/right (LR) body asymmetry during development. Cilia play a key role in this process, and candidate genes for dyslexia have also been...

Topics

Animals
Central Nervous System Diseases
Cilia
Dyslexia
Functional Laterality
Genetic Predisposition to Disease
Humans
Proprotein Convertases
Serine Endopeptidases

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Identifiers

PMID: 24275328
DOI: 10.1016/j.molmed.2013.10.008
PMCID: PMC3969300

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