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Article

Genetic variants associated with development of TMD and its intermediate phenotypes: the genetic architecture of TMD in the OPPERA prospective cohort study.

The journal of pain - 1 Dec 2013

Smith Shad B, Mir Ellen, Bair Eric, Slade Gary D, Dubner Ronald, Fillingim Roger B, Greenspan Joel D, Ohrbach Richard, Knott Charles, Weir Bruce, Maixner William, Diatchenko Luda

Abstract excerpt

UNLABELLED: Genetic risk factors are believed to combine with environmental exposures and contribute to the risk of developing temporomandibular disorder (TMD). In this prospective cohort study, 2,737 people without TMD were assessed for common genetic variation in 358 genes known to contribute to nociceptive pathways, inflammation, and affective distress. During a median follow-up period of 2.8 years, 260 people...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Share to Temporomandibular Joint Disorders

Source

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Identifiers

PMID: 24275226
DOI: 10.1016/j.jpain.2013.09.004
PMCID: PMC3855664

Genes

ACE2
APP
MPDZ
PTGS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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