Article
<i>F2RL3</i> Methylation as a Biomarker of Current and Lifetime Smoking Exposures
22 Nov 2013
Abstract excerpt
BACKGROUND: Recent genome-wide DNA methylation studies have found a pronounced difference in methylation of the F2RL3 gene (also known as PAR-4) in blood DNA according to smoking exposure. Knowledge on the variation of F2RL3 methylation by various degrees of smoking exposure is still very sparse. OBJECTIVES: We aimed to assess dose-response relationships of current and lifetime active smoking exposure with F2RL3...
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