Article
COX-2 is associated with periodontitis in Europeans.
Journal of dental research - 1 Apr 2010
Schaefer A S, Richter G M, Nothnagel M, Laine M L, Noack B, Glas J, Schrezenmeir J, Groessner-Schreiber B, Jepsen S, Loos B G, Schreiber S
Abstract excerpt
COX-2 plays an important role in periodontitis by mediating inflammatory reactions in periodontal tissues, and the COX-2 polymorphisms rs20417 and rs689466 have been reported to be associated with periodontitis in populations of Taiwanese and Chinese ethnicity. To test whether these variants were associated with periodontitis in populations of European ethnicity, we genotyped the single-nucleotide polymorphisms...
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