Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Homozygosity in the ApoE 4 polymorphism is associated with dysphagic symptoms in older adults.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jan 2015

Mentz H, Horan M, Payton A, Ollier W, Pendleton N, Hamdy S

Abstract excerpt

Apolipoprotein E (ApoE) is the most well-described genetic risk factor for Alzheimer's disease and nonpathological cognitive decline. While possession of the E2 allele may have protective properties, substantial research evidence suggests the E4 allele increases the risk of cognitive degeneration. As neurodegenerative processes are implicated in swallowing dysfunction, we hypothesized that the presence of ApoE 4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognition

Share to Deglutition Disorders

Share to Depression

Share to Gene Frequency

Share to Homozygote

Share to Self Report

Source

Identifiers

PMID: 24261350
DOI: 10.1111/dote.12162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Homozygosity in the ApoE 4 polymorphism is associated with dysphagic symptoms in older adults.PMID 24261350Read ↗

Genetic determinants of swallowing impairments among community dwelling older population.Semantic proximity Read ↗

APOE4 homozygosity represents a distinct genetic form of Alzheimer’s diseaseSemantic proximity Read ↗

Association analysis of apolipoprotein E genotype and risk of depressive symptoms in Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E e4 Allele Is Associated with Subjective Cognitive Decline: A Meta-Analysis.Semantic proximity Read ↗

APOE E4 is associated with cognitive decline but not with disease risk or age of onset in Nigerians with Parkinson’s diseaseSemantic proximity Read ↗

APOE genotype influences functional status among elderly without dementia.Semantic proximity Read ↗

Neuropsychiatric symptoms and ApoE genotype in older adults without dementia: a cross-sectional study.Semantic proximity Read ↗

Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis.Semantic proximity Read ↗

A novel mutation in the apolipoprotein E gene (APOE*4 Pittsburgh) is associated with the risk of late-onset Alzheimer's diseaseSemantic proximity Read ↗

Role of APOE genotype in gait decline and disability in aging.Semantic proximity Read ↗

A longitudinal study of apolipoprotein-E genotype and depressive symptoms in community-dwelling older adults.Semantic proximity Read ↗

APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.