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Article

Assessment of type 1 diabetes risk conferred by HLA-DRB1, INS-VNTR and PTPN22 genes using the Bayesian network approach.

PloS one - 1 Jan 2013

Portuesi Rosalba, Pozzilli Paolo, Boehm Bernhard, Buzzetti Raffaella, Filippi Simonetta

Abstract excerpt

BACKGROUND: Determining genetic risk is a fundamental prerequisite for the implementation of primary prevention trials for type 1 diabetes (T1D). The aim of this study was to assess the risk conferred by HLA-DRB1, INS-VNTR and PTPN22 single genes on the onset of T1D and the joint risk conferred by all these three susceptibility loci using the Bayesian Network (BN) approach in both population-based case-control...

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Source

Open in PubMed Open full text

Identifiers

PMID: 24260237
DOI: 10.1371/journal.pone.0079506
PMCID: PMC3832602

Genes

INS
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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