Article
RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans.
Open biology - 20 Nov 2013
Akay Alper, Craig Ashley, Lehrbach Nicolas, Larance Mark, Pourkarimi Ehsan, Wright Jane E, Lamond Angus, Miska Eric, Gartner Anton
Abstract excerpt
Messenger RNA translation is regulated by RNA-binding proteins and small non-coding RNAs called microRNAs. Even though we know the majority of RNA-binding proteins and microRNAs that regulate messenger RNA expression, evidence of interactions between the two remain elusive. The role of the RNA-binding protein GLD-1 as a translational repressor is well studied during Caenorhabditis elegans germline development and...
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