Article
Frequency and predictors of HIV-1 co-receptor switch in treatment naive patients.
PloS one - 1 Jan 2013
Mortier Virginie, Dauwe Kenny, Vancoillie Leen, Staelens Delfien, Van Wanzeele Filip, Vogelaers Dirk, Vandekerckhove Linos, Chalmet Kristen, Verhofstede Chris
Abstract excerpt
BACKGROUND: Determination of HIV-1 co-receptor use is a necessity before initiation of a CCR5 antagonist but the longevity of a CCR5-use prediction remains unknown. METHODS: Genotypic co-receptor tropism determination was performed in 225 newly diagnosed individuals consulting an AIDS Reference Centre. Samples were collected at diagnosis and at initiation of antiretroviral therapy or just before closure of the...
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