Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evolution of a genetic diagnosis.

Clinical genetics - 1 Dec 2014

Laksman Z, Dulay D, Gollob M H, Skanes A C, Krahn A D

Abstract excerpt

Understanding the relationship between genotype and phenotype has become an integral part of the diagnosis and management of patients with inherited arrhythmias and cardiomyopathies. Given the existence of background noise, the majority of genetic testing results should be incorporated into clinical decision making as probabilistic, rather than deterministic, in the diagnosis and management of inherited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrhythmias, Cardiac
Share to Cardiomyopathies
Share to Death, Sudden, Cardiac

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrocardiography

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Potassium Channels, Inwardly Rectifying

Share to Ryanodine Receptor Calcium Release Channel

Source

Identifiers

PMID: 24237251
DOI: 10.1111/cge.12320

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Evolution of a genetic diagnosis.PMID 24237251Read ↗

Genetic Testing in Inherited Arrhythmias: Approach, Limitations, and Challenges.Semantic proximity Read ↗

The evolution of gene-guided management of inherited arrhythmia syndromes: Peering beyond monogenic paradigms towards comprehensive genomic risk scores.Semantic proximity Read ↗

Genetic testing in heritable cardiac arrhythmia syndromes: differentiating pathogenic mutations from background genetic noise.Semantic proximity Read ↗

Genetic testing and genetic counseling in patients with sudden death risk due to heritable arrhythmiasSemantic proximity Read ↗

Genetic diseases: How the noise fits in.Semantic proximity Read ↗

Conveying a probabilistic genetic test result to families with an inherited heart diseaseSemantic proximity Read ↗

Communication of genetic information to families with inherited rhythm disorders.Semantic proximity Read ↗

A Proposed North American Approach for Genetic Testing of Individuals at Risk for Malignant Hyperthermia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.