Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.

doi:10.2217/pgs.13.166

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Genome-wide association study in NSAID-induced acute urticaria/angioedema in Spanish and Han Chinese populations.

Pharmacogenomics - 1 Nov 2013

Cornejo-García José Antonio, Liou Lieh-Bang, Blanca-López Natalia, Doña Inmaculada, Chen Chien-Hsiun, Chou Yi-Chun, Chuang Hui-Ping, Wu Jer-Yuarn, Chen Yuan-Tsong, Plaza-Serón María Del Carmen, Mayorga Cristobalina, Guéant-Rodríguez Rosa María, Lin Shih-Chang, Torres María José, Campo Paloma, Rondón Carmen, Laguna José Julio, Fernández Javier, Guéant Jean-Louis, Canto Gabriela, Blanca Miguel, Lee Ming Ta Michael

Abstract excerpt

AIM: Acute urticaria/angioedema (AUA) induced by cross-intolerance to NSAIDs is the most frequent clinical entity in hypersensitivity reactions to drugs. In this work, we conducted a genome-wide association study in Spanish and Han Chinese patients suffering from NSAID-induced AUA. MATERIALS & METHODS: A whole-genome scan was performed on a total of 232 cases (112 Spanish and 120 Han Chinese) with NSAID-induced...

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PMID: 24236485
DOI: 10.2217/pgs.13.166

Genes

BICC1
HLF
RIMS1

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