Article
Association of HDL-related loci with age-related macular degeneration and plasma lutein and zeaxanthin: the Alienor study.
PloS one - 1 Jan 2013
Merle Bénédicte M J, Maubaret Cécilia, Korobelnik Jean-François, Delyfer Marie-Noëlle, Rougier Marie-Bénédicte, Lambert Jean-Charles, Amouyel Philippe, Malet Florence, Le Goff Mélanie, Dartigues Jean-François, Barberger-Gateau Pascale, Delcourt Cécile
Abstract excerpt
BACKGROUND: Several genes implicated in high-density lipoprotein (HDL) metabolism have been reported to be associated with age-related macular degeneration (AMD). Furthermore, HDL transport the two carotenoids, lutein and zeaxanthin, which are highly suspected to play a key-role in the protection against AMD. The objective is to confirm the associations of HDL-related loci with AMD and to assess their...
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