Article
Comprehensive survey of HRAS, KRAS, and NRAS mutations in proliferative thyroid lesions from an ethnically diverse population.
Anticancer research - 1 Nov 2013
Schulten Hans-Juergen, Salama Sherine, Al-Ahmadi Alaa, Al-Mansouri Zuhoor, Mirza Zeenat, Al-Ghamdi Khalid, Al-Hamour Osman Abdel, Huwait Etimad, Gari Mamdooh, Al-Qahtani Mohammad Hussain, Al-Maghrabi Jaudah
Abstract excerpt
BACKGROUND: The distribution and kind of rat sarcoma viral oncogenes homolog (RAS) mutations, as well as their clinical impact on different types of thyroid lesions, vary widely among the different populations studied. We performed a comprehensive mutational survey in the highly related RAS genes HRAS, KRAS, and NRAS in a case series of proliferative thyroid lesions with known BRAF mutational status, originating...
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