The genetic association between PON1 polymorphisms and osteonecrosis of femoral head: A case-control study.

doi:10.1097/MD.0000000000008198

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Article

The genetic association between PON1 polymorphisms and osteonecrosis of femoral head: A case-control study.

Medicine - 1 Oct 2017

Li Jian-Mei, Li Yi, Wang Lu

Abstract excerpt

The purpose of this study was to investigate the relationship between Paraoxonase-1 (PON1) gene rs662, rs854555 polymorphisms and osteonecrosis of the femoral head (ONFH) in Han population, northern China.Polymerase chain reaction-restriction fragment length polymorphism was used to determine genotypes of PON1 polymorphisms in 84 patients with ONFH and 96 healthy persons. χ test was used to compare distribution...

Topics

Adult
Aged
Alleles
Aryldialkylphosphatase
Asian People
Case-Control Studies
Chi-Square Distribution
China
Female
Femur Head Necrosis
Gene Frequency
Genetic Association Studies
Genetic Predisposition to Disease
Genotype
Haplotypes
Humans
Linkage Disequilibrium
Logistic Models

Source

Open in PubMed Open full text

Identifiers

PMID: 29049204
DOI: 10.1097/MD.0000000000008198
PMCID: PMC5662370

Genes

PON1

Provenance

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