Article
The role of androgen receptor gene in cyclosporine induced gingival overgrowth.
Journal of periodontal research - 1 Oct 2014
Al Sayed A A, Al Sulaiman M H, Mishriky A, Anil S
Abstract excerpt
BACKGROUND AND OBJECTIVE: Gingival overgrowth is a prominent side effect of cyclosporine (CsA) therapy in renal transplant patients. Although the exact mechanism by which this drug induces gingival overgrowth is uncertain, marked variations in individual susceptibility to this drug suggest a genetic predisposition. Studies have shown that genetic variation (polymorphism) in the trinucleotide cytosine-adenine-...
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