Article
Possible association of CTLA-4 gene polymorphism with cyclosporine-induced gingival overgrowth in kidney transplant recipients.
Transplantation proceedings - 1 Nov 2007
Kusztal M, Radwan-Oczko M, Kościelska-Kasprzak K, Boratyńska M, Patrzałek D, Klinger M
Abstract excerpt
T-lymphocytes may play a role in the pathogenesis of inflammatory periodontal diseases and cyclosporine (CsA)-induced gingival overgrowth (GO). The gene encoding CTLA-4 (Cytotoxic T-lymphocyte antigen 4, a molecule influencing T-cell activation), is known to have a single nucleotide polymorphism...
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