Article
Alpha 2 integrin gene (ITGA2) polymorphism in renal transplant recipients with and without drug induced gingival overgrowth.
Archives of oral biology - 1 Mar 2014
Gürkan Ali, Emingil Gülnur, Afacan Beral, Berdeli Afig, Atilla Gül
Abstract excerpt
BACKGROUND: Variances in fibroblasts' α2β1 integrin intensity may lead to altered adhesion to type I collagen and consequently to suppression of phagocytosis which may be one of the mechanisms for drug induced gingival overgrowth. The present study aimed to evaluate the genotype and allele frequencies of α2 integrin +807 gene in renal transplant patients with and without gingival overgrowth. MATERIAL AND METHODS:...
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