Article
Regulation of Staphylococcus aureus MntC expression and its role in response to oxidative stress.
PloS one - 1 Jan 2013
Handke Luke D, Hawkins Julio C, Miller Alita A, Jansen Kathrin U, Anderson Annaliesa S
Abstract excerpt
Staphylococcus aureus is a successful human pathogen that has developed several approaches to evade the immune system, including resistance strategies to prevent oxidative killing by immune cells. One mechanism by which this evasion occurs is by production of superoxide dismutase enzymes, which require manganese as a cofactor. Manganese is acquired by the manganese transporter MntABC. One component of this...
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