Article
The immune system GTPase GIMAP6 interacts with the Atg8 homologue GABARAPL2 and is recruited to autophagosomes.
PloS one - 1 Jan 2013
Pascall John C, Rotondo Sergio, Mukadam Aamir S, Oxley David, Webster Judith, Walker Simon A, Piron Jerry, Carter Christine, Ktistakis Nicholas T, Butcher Geoffrey W
Abstract excerpt
The GIMAPs (GTPases of the immunity-associated proteins) are a family of small GTPases expressed prominently in the immune systems of mammals and other vertebrates. In mammals, studies of mutant or genetically-modified rodents have indicated important roles for the GIMAP GTPases in the development and survival of lymphocytes. No clear picture has yet emerged, however, of the molecular mechanisms by which they...
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