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Article

Functional insights into recombinant TROSPA protein from Ixodes ricinus.

PloS one - 1 Jan 2013

Figlerowicz Marek, Urbanowicz Anna, Lewandowski Dominik, Jodynis-Liebert Jadwiga, Sadowski Czeslaw

Abstract excerpt

Lyme disease (also called borreliosis) is a prevalent chronic disease transmitted by ticks and caused by Borrelia burgdorferi s. l. spirochete. At least one tick protein, namely TROSPA from I. scapularis, commonly occurring in the USA, was shown to be required for colonization of the vector by bacteria. Located in the tick gut, TROSPA interacts with the spirochete outer surface protein A (OspA) and initiates the...

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Identifiers

PMID: 24204685
DOI: 10.1371/journal.pone.0076848
PMCID: PMC3800121

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Source receipt: pubmed, retrieved 7 Sept 2026.

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