Article
Interaction of genetic risk factors confers increased risk for metabolic syndrome: the role of peroxisome proliferator-activated receptor γ.
Genetic testing and molecular biomarkers - 1 Jan 2014
Božina Tamara, Sertić Jadranka, Lovrić Jasna, Jelaković Bojan, Šimić Iveta, Reiner Željko
Abstract excerpt
AIM: The aim of the study was to estimate the influence of interactions between peroxisome proliferator-activated receptor γ (PPARγ) and target genes lipoprotein lipase (LPL), interleukin 6 (IL6), angiotensin converting enzyme (ACE), and angiotensin II type 1 receptor (AT1R) on metabolic syndrome (MetSy) and its traits. METHODS: The study included 527 participants (263 with MetSy and 264 controls). Genotyping of...
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