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Article

Oncogenic function of SCCRO5/DCUN1D5 requires its Neddylation E3 activity and nuclear localization.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jan 2014

Bommeljé Claire C, Weeda Víola B, Huang Guochang, Shah Kushyup, Bains Sarina, Buss Elizabeth, Shaha Manish, Gönen Mithat, Ghossein Ronald, Ramanathan Suresh Y, Singh Bhuvanesh

Abstract excerpt

PURPOSE: To determine mechanisms by which SCCRO5 (aka DCUN1D5) promotes oncogenesis. EXPERIMENTAL DESIGN: SCCRO5 mRNA and protein expression were assessed in 203 randomly selected primary cancer tissue samples, matched histologically normal tissues, and cell lines by use of real-time PCR and Western blot analysis. SCCRO5 overexpression was correlated with survival. The effect of SCCRO5 knockdown on viability was...

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Identifiers

PMID: 24192928
DOI: 10.1158/1078-0432.CCR-13-1252
PMCID: PMC4191716

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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