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Age, Sexual Dimorphism, and Disease Associations in the Developing Human Fetal Lung Transcriptome

19 Nov 2015

Abstract excerpt

The fetal origins of disease hypothesis suggests that variations in the course of prenatal lung development may affect life-long pulmonary function growth, decline, and pathobiology. Many studies support the existence of differences in the developing lung trajectory in males and females, and sex-specific differences in the prevalence of chronic lung diseases, such as asthma and bronchopulmonary dysplasia. The...

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PMID: 26584061
DOI: 10.1165/rcmb.2015-0326oc

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