Article
The genomic origins of asthma.
Thorax - 1 May 2014
Sharma Sunita, Chhabra Divya, Kho Alvin T, Hayden Lystra P, Tantisira Kelan G, Weiss Scott T
Abstract excerpt
Lung function tracks from the earliest age that it can be reliably measured. Genome wide association studies suggest that most variants identified for common complex traits are regulatory in function and active during fetal development. Fetal programming of gene expression during development is critical to the formation of a normal lung. An understanding of how fetal developmental genes related to diseases of the...
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