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Article

Role of the Trypanosoma brucei HEN1 family methyltransferase in small interfering RNA modification.

Eukaryotic cell - 1 Jan 2014

Shi Huafang, Barnes Rebecca L, Carriero Nicholas, Atayde Vanessa D, Tschudi Christian, Ullu Elisabetta

Abstract excerpt

Parasitic protozoa of the flagellate order Kinetoplastida represent one of the deepest branches of the eukaryotic tree. Among this group of organisms, the mechanism of RNA interference (RNAi) has been investigated in Trypanosoma brucei and to a lesser degree in Leishmania (Viannia) spp. The pathway is triggered by long double-stranded RNA (dsRNA) and in T. brucei requires a set of five core genes, including a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24186950
DOI: 10.1128/EC.00233-13
PMCID: PMC3910962

Genes

AGO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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