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Immunoregulatory function of mesenchymal stem cells

1 Oct 2006

Abstract excerpt

Mesenchymal stem cells (MSC) are a rare subset of stem cells residing in the bone marrow where they closely interact with hematopoietic stem cells and support their growth and differentiation. MSC can differentiate into multiple mesenchymal and non-mesenchymal lineages, providing a promising tool for tissue repair. In addition, MSC suppress many T cell, B cell and NK cell functions and may affect also dendritic...

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PMID: 17013987
DOI: 10.1002/eji.200636416

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