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Article

Reselection of a genomic upstream open reading frame in mouse hepatitis coronavirus 5'-untranslated-region mutants.

Journal of virology - 1 Jan 2014

Wu Hung-Yi, Guan Bo-Jhih, Su Yu-Pin, Fan Yi-Hsin, Brian David A

Abstract excerpt

An AUG-initiated upstream open reading frame (uORF) encoding a potential polypeptide of 3 to 13 amino acids (aa) is found within the 5' untranslated region (UTR) of >75% of coronavirus genomes based on 38 reference strains. Potential CUG-initiated uORFs are also found in many strains. The AUG-initiated uORF is presumably translated following genomic 5'-end cap-dependent ribosomal scanning, but its function is...

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Identifiers

PMID: 24173235
DOI: 10.1128/JVI.02831-13
PMCID: PMC3911626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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