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Article

A U-turn motif-containing stem-loop in the coronavirus 5' untranslated region plays a functional role in replication.

RNA (New York, N.Y.) - 1 May 2007

Liu Pinghua, Li Lichun, Millership Jason J, Kang Hyojeung, Leibowitz Julian L, Giedroc David P

Abstract excerpt

The 5' untranslated region (UTR) of the mouse hepatitis virus (MHV) genome contains cis-acting sequences necessary for transcription and replication. A consensus secondary structural model of the 5' 140 nucleotides of the 5' UTRs of nine coronaviruses (CoVs) derived from all three major CoV groups is presented and characterized by three major stem-loops, SL1, SL2, and SL4. NMR spectroscopy provides structural...

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Source

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Identifiers

PMID: 17353353
DOI: 10.1261/rna.261807
PMCID: PMC1852815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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