Article
Characterization of an essential RNA secondary structure in the 3' untranslated region of the murine coronavirus genome.
Journal of virology - 1 Aug 2000
Hsue B, Hartshorne T, Masters P S
Abstract excerpt
We have previously identified a functionally essential bulged stem-loop in the 3' untranslated region of the positive-stranded RNA genome of mouse hepatitis virus. This 68-nucleotide structure is composed of six stem segments interrupted by five bulges, and its structure, but not its primary sequence, is entirely conserved in the related bovine coronavirus. The functional importance of individual stem segments of...
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