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Article

The Presence of SDHB Mutations Should Modify Surgical Indications for Carotid Body Paragangliomas

30 Oct 2013

Abstract excerpt

OBJECTIVE: The aim of this study was to determine whether the genetic background of the disease should be incorporated into treatment decision making. BACKGROUND: Carotid body paragangliomas are rare tumors that often affect patients with genetic mutations of the succinate dehydrogenase complex (SDHx). Despite growing evidence that germ line genetic mutations alter the aggressiveness of paragangliomas, treatment...

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PMID: 24169168
DOI: 10.1097/sla.0000000000000283

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