Article
Succinate dehydrogenase mutations in head and neck paragangliomas: A systematic review and meta-analysis of individual patients' data.
Head & neck - 1 Jul 2024
Koh Elizabeth S, Dabsha Anas, Rahouma Mohamed, Zappi Kyle, Srinivasan Yashes, Hickner Andy, Kutler David I
Abstract excerpt
BACKGROUND: Head and neck paragangliomas (HNPs) have been associated with gene mutations in the succinate dehydrogenase (SDH) complex, but the clinical significance remains unclear. We sought to explore the demographics, clinical characteristics, treatment methods, and outcomes of SDH-mutated HNPs. METHODS: Databases were systematically searched. Pooled event ratio and relative 95% confidence intervals were...
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