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Article

Pilot study of association of catechol-O-methyl transferase rs4680 genotypes with acute kidney injury and tubular stress after open heart surgery.

Biomarkers in medicine - 1 Jan 2014

Albert Christian, Kube Johanna, Haase-Fielitz Anja, Dittrich Annemarie, Schanze Denny, Zenker Martin, Kuppe Hermann, Hetzer Roland, Bellomo Rinaldo, Mertens Peter R, Haase Michael

Abstract excerpt

AIM: To assess the association of genetic variants of catecholamine-O-methyltransferase (COMT) genotypes with acute kidney injury (AKI) and tubular stress after open heart surgery. PATIENTS & METHODS: We genotyped 195 patients for the COMT-Val158Met polymorphism and measured creatinine, neutrophi...

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Source

Identifiers

PMID: 25525983
DOI: 10.2217/bmm.14.85

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25525983-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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