Article
Genome-wide linkage and positional association study of blood pressure response to dietary sodium intervention: the GenSalt Study.
American journal of epidemiology - 1 Oct 2012
Mei Hao, Gu Dongfeng, Hixson James E, Rice Treva K, Chen Jing, Shimmin Lawrence C, Schwander Karen, Kelly Tanika N, Liu De-Pei, Chen Shufeng, Huang Jian-feng, Jaquish Cashell E, Rao Dabeeru C, He Jiang
Abstract excerpt
The authors conducted a genome-wide linkage scan and positional association analysis to identify the genetic determinants of salt sensitivity of blood pressure (BP) in a large family-based, dietary-feeding study. The dietary intervention was conducted among 1,906 participants in rural China (2003-2005). A 7-day low-sodium intervention was followed by a 7-day high-sodium intervention. Salt sensitivity was defined...
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