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Article

Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample.

Alcoholism, clinical and experimental research - 1 Nov 2013

Meyers Jacquelyn L, Shmulewitz Dvora, Aharonovich Efrat, Waxman Rachel, Frisch Amos, Weizman Abraham, Spivak Baruch, Edenberg Howard J, Gelernter Joel, Hasin Deborah S

Abstract excerpt

BACKGROUND: Alcohol dehydrogenase 1B and 1C (ADH1B and ADH1C) variants have been robustly associated with alcohol phenotypes in East Asian populations, but less so in non-Asian populations where prevalence of the most protective ADH1B allele is low (generally <5%). Further, the joint effects of ADH1B and ADH1C on alcohol phenotypes have been unclear. Therefore, we tested the independent and joint effects of ADH1B...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23895337
DOI: 10.1111/acer.12176
PMCID: PMC3812252

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