Article
Novel B-cell acute lymphoblastic leukemia sister cell lines BALM 19-23 and BALM-26 with interclonal proliferative and phenotypic heterogeneity from a patient with hypercalcemia.
Human cell - 1 Sept 2002
Matsuo Yoshinobu, Drexler Hans G, Kojima Kensuke, Sugimoto Akira, Harashima Akira, Okochi Ayumi, Hara Masamichi, Orita Kunzo
Abstract excerpt
A series of human acute lymphoblastic leukemia (ALL) cell lines, BALM-19, -20, -21, -22, -23 (BALM 19-23) and BALM-26 were established from a patient with B-cell characteristics of ALL L2 type. All cell lines were derived from bone marrow specimens, BALM 19-23 from a sample taken at diagnosisand BALM-26 from one at relapse. Like the original leukemia cells, the established lines present various B-cell...
Topics
- Adult
- Antigens, CD
- Burkitt Lymphoma
- Genetic Heterogeneity
- Humans
- Hypercalcemia
- Male
- Parathyroid Hormone-Related Protein
- Peptide Hormones
- Phenotype
- Tumor Cells, Cultured