Article
Comprehensive analysis of oncogenic mutations in lung squamous cell carcinoma with minor glandular component.
Chest - 1 Mar 2014
Pan Yunjian, Wang Rui, Ye Ting, Li Chenguang, Hu Haichuan, Yu Yongfu, Zhang Yang, Wang Lei, Luo Xiaoyang, Li Hang, Li Yuan, Shen Lei, Sun Yihua, Chen Haiquan
Abstract excerpt
BACKGROUND: The mutations in oncogenic genes, such as EGFR, ALK, BRAF, HER2, DDR2, RET, and AKT1, defined subsets of non-small cell lung cancers (NSCLCs) with potential sensitivity to targeted therapies. At present, the mutational spectrum, prevalence, and clinicopathologic characteristics in squamous cell carcinomas with minor (<10%) glandular component (SQCC-mGCs) are not well established. METHODS: Three...
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