Article
Statin therapy correlated CYP2D6 gene polymorphism and hyperlipidemia.
Current medical research and opinion - 1 Feb 2014
Li Juyi, Wang Xiufang, Zhang Zhaoqing, Zou Jili, Chen Yonggang, Wang Xiong, Wu Jinhu
Abstract excerpt
PURPOSE: To investigate the distribution of statin therapy correlated gene polymorphism allele CYP2D6*10 (C188T) in Ningxia Hui nationality and to discuss the relationship between the gene polymorphism allele CYP2D6*10 (C188T) and the lipid-lowering efficacy of simvastatin and hyperlipidemia. MATERIALS AND METHODS: One hundred and fifty healthy people (80 males and 70 females) and 200 hyperlipidemia patients (105...
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