Human genome-guided identification of memory-modulating drugs.

doi:10.1073/pnas.1314478110

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Article

Human genome-guided identification of memory-modulating drugs.

Proceedings of the National Academy of Sciences of the United States of America - 12 Nov 2013

Papassotiropoulos Andreas, Gerhards Christiane, Heck Angela, Ackermann Sandra, Aerni Amanda, Schicktanz Nathalie, Auschra Bianca, Demougin Philippe, Mumme Eva, Elbert Thomas, Ertl Verena, Gschwind Leo, Hanser Edveena, Huynh Kim-Dung, Jessen Frank, Kolassa Iris-Tatjana, Milnik Annette, Paganetti Paolo, Spalek Klara, Vogler Christian, Muhs Andreas, Pfeifer Andrea, de Quervain Dominique J-F

Abstract excerpt

In the last decade there has been an exponential increase in knowledge about the genetic basis of complex human traits, including neuropsychiatric disorders. It is not clear, however, to what extent this knowledge can be used as a starting point for drug identification, one of the central hopes of the human genome project. The aim of the present study was to identify memory-modulating compounds through the use of...

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PMID: 24145423
DOI: 10.1073/pnas.1314478110
PMCID: PMC3831994

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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