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Article

Accurate measurement of gene copy number for human alpha-defensin DEFA1A3.

BMC genomics - 20 Oct 2013

Khan Fayeza F, Carpenter Danielle, Mitchell Laura, Mansouri Omniah, Black Holly A, Tyson Jess, Armour John A L

Abstract excerpt

BACKGROUND: Multi-allelic copy number variants include examples of extensive variation between individuals in the copy number of important genes, most notably genes involved in immune function. The definition of this variation, and analysis of its impact on function, has been hampered by the technical difficulty of large-scale but accurate typing of genomic copy number. The copy-variable alpha-defensin locus...

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Identifiers

PMID: 24138543
DOI: 10.1186/1471-2164-14-719
PMCID: PMC4046698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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