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Article

Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behçet's syndrome patients.

International immunology - 1 Feb 2014

Yüksel Şahru, Eren Elif, Hatemi Gülen, Sahillioğlu Ali Can, Gültekin Yetiş, Demiröz Duygu, Akdiş Cezmi, Fresko İzzet, Özören Nesrin

Abstract excerpt

Behçet's syndrome (BS) is a systemic inflammatory disorder with unknown etiology. Features of both innate and adaptive immunity have been claimed in the pathogenesis of BS. To test the possible dysregulation of the NLRP3/cryopyrin (Nod-like receptor with a pyrin domain 3) inflammasome, as a result of mutation(s), we performed single-strand conformation polymorphism analyses and/or sequencing of all the coding...

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Identifiers

PMID: 24135410
DOI: 10.1093/intimm/dxt046

Genes

NLRP3
TNF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Novel NLRP3/cryopyrin mutations and pro-inflammatory cytokine profiles in Behçet's syndrome patients.PMID 24135410Read ↗

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